Blood Collection Tube Additive Heparin Sodium 9041-08-1

Product Description

Packaging Specification : 10g/bottle,20g/bottle,50g/bottle

Basic Information
 

Appearance	White crystal powder
Place of Origin	Ezhou City, Hubei Province
Absorbance	260nm≤0.10
Dissolution	Easily soluble in water
Titer	150IU/mg
Main use	Used as an external anticoagulant for blood

Heparin sodium, an anticoagulant, is a mucopolysaccharide. It is a sodium salt of glucosamine sulfate extracted from the intestinal mucosa of pigs, cattle and sheep. It is secreted by mast cell in the human body and naturally exists in the blood. Heparin sodium has the function of preventing platelet aggregation and destruction, inhibiting the transformation of fibrinogen into fibrin monomers, inhibiting the formation of thromboplastin and antagonizing the formed thromboplastin, preventing the transformation of prothrombin into thrombin, and antagonizing thrombin.
   

Anticoagulant mechanism

Heparin sodium can delay or prevent blood clotting both in vivo and in vitro. Its mechanism of action is extremely complex and has an impact on many aspects of the coagulation process. Its function is:
1,to inhibit the formation and action of coagulation activating enzymes, thereby preventing the transformation of prothrombin into thrombin;
2,At high concentrations, it has the effect of inhibiting thrombin and other coagulation factors, hindering the transformation of fibrinogen into fibrin;
3,It can prevent the aggregation and destruction of platelet chemobooks. In addition, the anticoagulant effect of heparin sodium is still related to the negatively charged sulfate ions in its molecules. Positive charged alkaline substances such as protamine or toluidine blue can neutralize its negative charge, thus inhibiting its anticoagulant effect. Due to the activation and release of lipoprotein esterase by heparin in the body, it hydrolyzes the triglycerides and low-density lipoprotein of chyle particles, resulting in a lipid-lowering effect.
 

Physical and chemical properties

Heparin sodium is a white or almost white powder, odorless, hygroscopic, easily soluble in water, insoluble in organic solvents such as ethanol and acetone. In aqueous solutions, there is a strong negative charge that can form molecular complexes with some cations. The aqueous solution is relatively stable at pH 7.
 

Full series of blood collection additives produced by Desheng
 

Order number	Product name	CAS Number
1	Serum Separating Gel	/
2	Sodium Heparin	9041-08-1
3	Lithium Heparin	9045-22-1
4	EDTA K2	25102-12-9
5	EDTA K3	65501-24-8
6	EDTA Na2	6381-92-6
7	Blood Clot Activation	/
8	Blood Clot powder	/
9	Water Soluble Silicone Release Agent	/
10	High effective Silicone release agent	/
11	Potassium oxalate monohydrate	6487-48-5
12	Trisodium citrate dihydrate	6132-04-3

Company Introduction

Hubei New Desheng Material Technology Co., Ltd. specializes in the production of blood collection tube additives, chemiluminescent reagents, biological buffers, chromogenic substrates, enzyme preparations, antigen antibodies and other biochemical reagents. Founded in 2005, Desheng has a professional R&D team and advanced production equipment!