| Customization: | Available |
|---|---|
| CAS No.: | 77-86-1 |
| Formula: | C4h11no3 |
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Trimethylolaminomethane, or tris base for short, is a commonly used alkaline biobuffer. Its chemical formula is C4H11NO3 and its molecular weight is 121.14 g/mol. trimethylolaminomethane is a white crystalline solid powder, soluble in water, ethanol, etc., slightly soluble in ethyl acetate, and largely insoluble in non-polar solvents such as petroleum ether and benzene.
Tris(hydroxymethyl)aminomethane has a wide range of applications in biochemistry and pharmacology. It is an important amino acid derivative that can be used as a buffer and pH adjuster in biochemical reactions, as well as a raw material for pharmaceutical and medical purposes. In the food industry, TMA is also used as an emulsifier, stabiliser, thickener and flavouring agent. Tris(hydroxymethyl)aminomethane also has good biocompatibility and low toxicity, and is used in a wide range of medical, cosmetic and household chemical applications.
| CAS Number | 77-86-1 |
| Molecular Formula | C4H11NO3 |
| Molecular Weight | 121.14 |
| EINECS | 201-064-4 |
| Appearance | White Powder |
| Melting Point | 167-172 °C(lit.) |
| Storage conditions | room temp |
Tris is widely used in the preparation of buffer solutions in biochemical and molecular biology experiments. For example, the commonly used TAE and TBE buffer solutions (used for nucleic acid dissolution) in biochemical experiments require Tris; Because it contains amino group, it can undergo Condensation reaction with aldehyde. The pH of Tris alkali aqueous solution is around 10.5. Generally, hydrochloric acid is added to adjust the pH value to the desired value to obtain a buffer solution with that pH value. However, attention should also be paid to the effect of temperature on the pKa of Tris. Since Tris buffer is a weakly alkaline Chemicalbook solution, DNA will be Deprotonation in such a solution, thus improving its solubility. People often add EDTA to Tris hydrochloric acid buffer to make "TE buffer", and TE buffer is used to stabilize and store DNA. If the acid solution used to adjust the pH value is replaced with acetic acid, a "TAE buffer" (Tris/Acetate/EDTA) is obtained, while replacing it with boric acid results in a "TBE buffer" (Tris/Borate/EDTA). These two types of buffers are commonly used in nucleic acid electrophoresis experiments.
Each buffer developed has a specific buffer capacity and buffer range. Buffer capacity is the amount of acid or base that can be added before a significant change in pH begins. It can also be defined as the amount of strong acid or strong base that must be added to change the pH value of one liter of solution by one pH unit. After adding acidic or alkaline components, it plays a role in resisting pH changes. Maintain a relatively stable pH value of the solution by neutralizing a small amount of added acid or base.
Desheng is a manufacturer of industrial grade biological buffering agents, currently producing dozens of buffering agents that can be used in various industries.
Hubei New Desheng Material Technology Co., Ltd. specializes in the production of blood collection tube additives, chemiluminescent reagents, biological buffers, chromogenic substrates, enzyme preparations, antigen antibodies and other biochemical reagents. Founded in 2005, Desheng has a professional R&D team and advanced production equipment!
Question:Who are we?
Answer:We are Hubei Xindesheng Material Technology Co., Ltd., a professional manufacturer of in vitro diagnostic reagent raw materials.
Question:Where is the company?
Answer:Huarong District, Ezhou City, Hubei Province, is adjacent to Wuhan City.Welcome to visit the company!
Question:What is the delivery time?
Answer:It is determined based on the inventory status of the product and the production and delivery status on that day. Generally, if there is stock available, shipment will be arranged on the day of placing the order.
Question:How to choose the transportation method?
Answer:Determine based on the urgency of the customer's purchase of products and needs. When the quantity of products is low and the value is high, it is recommended to choose air freight or international express delivery; When there is a large quantity of products, choosing sea or land transportation is more cost-effective.
Question:What are the payment methods available?
Answer:T/T,LC, etc
Question:What are the regular packaging options?
Answer:500g/bottle, plastic bottle or 25kg/bucket, cardboard bucket.
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