Customization: | Available |
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CAS No.: | No |
Formula: | No |
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Gene Recombinant Protein Description: Uricase (EC 1.7.3.3), also known as uric acid oxidase, is extracted from fermentation broth of Aspergillus niger, Aspergillus flavus, and other fungi. It is a white freeze-dried powder or a gray white to brownish green crystalline or shiny transparent sheet, slightly soluble in alkaline buffer, with a pH value of 6.3. The enzyme activity is inhibited by cyanide, and inhibitors such as Ag+and Hg2+.
Dosage form: | White freeze-dried powder, or liquid | Molecular weight: | 35-40kDa(SDS-PAGE detection) |
Save buffer: | PBS,pH7.4 | Purity | ≥ 90% (SDS-PAGE detection) |
Enzyme activity: | 10 U/mg,dry powder | Transportation Conditions: | Low temperature, ice bag |
Source: | Gene recombination expression | Safety tips: | Not applicable for human experiments |
Vitality unit: | Oxidize 1% per minute at pH 8.5 and 37 ºC μ The amount of enzyme required for mol uric acid is defined as 1 U unit. | ||
Storage condition: | Freeze dried powder should be stored at 4 ºC for one year and -20 ºC for two years (it is recommended to store separately and avoid repeated freeze-thaw as much as possible) |
Clinical Biochemical Testing: Used for measuring uric acid levels in blood or urine in clinical biochemical testing, renal function reagent raw material enzyme, used in uric acid detection kit, is an enzyme that can catalyze the oxidation of uric acid to produce allantoin, carbon dioxide, and hydrogen peroxide.
1.High catalytic efficiency: Urinase can efficiently oxidize uric acid to allantoin, which is not only fast but also has a high conversion rate, making it very suitable for rapidly reducing uric acid levels in the body.
2.Strong specificity: Urinase has high specificity for uric acid, which means it can accurately catalyze uric acid without affecting other biomolecules, making it safer and more effective in medical applications.
3.Recombinant expression system: Using a recombinant expression system to produce uricase can reduce the complexity and cost of traditional extraction from natural sources such as Aspergillus niger, while also avoiding potential impurity issues that may arise from natural sources.