Madb Chromogenic Substrate CAS209518-16-1 High Purity White Powder

• Customization: Available
• CAS No.: 209518-16-1
• Formula: C16h25nna2o6s2
• Model NO.: MADB
• EINECS: Non
• Appearance: Powder
• Usage: in Vitro Diagnosis
• Color: White
• OEM Pakcing: Yes
• Purity: 99%
• Delivery Time: 3-5days
• Absorbing Wavelength: 630nm
• Storage: Avoid Light and Freeze Storage
• Colour: White
• Form: Powder
• Water Solubility: Soluble
• Storage Conditions: Protected From Light and Moist
• Transport Package: Bottle
• Specification: 10g/bottle
• Trademark: Desheng
• Origin: China

Product Description

Trinder's reagent MADB Chromogenic Substrate CAS209518-16-1
 

English name	N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt
Abbreviation	MADB
CAS#	209518-16-1
Molecular weight	437.48234
Molecular formula	C16H25NNa2O6S2
Storage condition	0-5ºC, away from light and moisture
Transportation Conditions	room temperature

Product advantageThe purity is >99%, with good water solubility and stable process, which can ensure that the product appearance is pure white crystal powder.
 

MADB Powder

ApplicationThis product can be used in the water-soluble reagent for the determination of hydrogen peroxid e by enzyme photometry, widely used in diagnosis and biochemical test.

The full name of the enzyme-linked immunosubstrate MADB is N,N-bis(4-sulfobutyl)-3,5-dimethylaniline sodium salt, a peroxidase chromogenic substrate with good hydrophilic properties. Its chromogenic product with 4-AAP has a maximum absorption wavelength of 630 nm and is suitable for the detection of samples with complex composition, e.g. for the enzymatic photometric triglyceride assay.

MADB is an ingredient in biochemical kits and is used as a chromogenic substrate for peroxidase. In the enzymatic photometric triglyceride kit, it is oxidised in the presence of peroxidase, which is coupled to 4-AAP. Triglycerides undergo a series of reactions to produce hydrogen peroxid e oxidation, which can produce a colour development reaction with MADB.

Enzyme immunoassay substrate MADB for the enzymatic triglyceride assay
Triglyceride assay principle:
During the assay, triglycerides are first hydrolysed to glycerol and fatty acids in the presence of lipoprotein esterase (LPL, lipoprotein lipase); glycerol and adenosine triphosphate ATP are catalysed by glycerol kinase (GK) to produce glycerol-3-phosphate and ADP; glycerol-3-phosphate and oxygen are catalysed by glycerol-3-phosphate oxidase (GPO) to produce dihydroxyacetone phosphate and hydrogen peroxid e; the hydrogen peroxid e generated is The hydrogen peroxid e generated can then be coupled to the chromogenic substrates MADB and 4-AAP to produce a quinonimine substance, which can then be detected by spectrophotometry at the maximum absorption wavelength of 630 nm, usually by the colourimetric endpoint method.

Triglycerides in relation to lipoproteins:

Triglycerides are esters formed from glycerol and 3 fatty acids and are the most abundant of the natural fats. In the blood, triglycerides bind to apolipoproteins to form very low density lipoproteins (VLDL) and celiac particles, which are transported throughout the body. Triglyceride testing is used to screen for fat status, to detect atherogenic risk and to monitor the effectiveness of lipid-lowering therapy. Recent studies have shown that an increase in triglycerides in combination with an increase in low-density lipoprotein (LDL) is associated with a high risk of coronary heart disease (CHD) in particular. Epidemiological studies have observed that the presence of serum triglycerides >2 mmol/L and high-density lipoprotein cholesterol (HDL-C) <1.0 mmol/L together indicates a high risk of future coronary heart disease (CHD). The clinical application of the triglyceride threshold (>2.3mmol/L) needs to be combined with other risk factors for CHD.

The new Trinder's reagents, including MADB, can be used for triglyceride testing as well as LDL testing or other biochemical tests. Desheng Trinder's reagents include MADB, MAOS, TOOS, DA64 and more than ten other substrates.

Company Introduction
Hubei New Desheng Material Technology Co., Ltd. specializes in the production of blood collection tube additives, chemiluminescent reagents, biological buffers, chromogenic substrates, enzyme preparations, antigen antibodies and other biochemical reagents. Founded in 2005, Desheng has a professional R&D team and advanced production equipment!

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